CVE record · CVE-2025-20281

Cisco ISE API Unauthenticated Remote Code Execution Vulnerability

CVSS 10.0 CriticalCriticalIn CISA KEVEPSS 0.98 · 99th percentile

Critical, because:

In CISA’s KEV catalogue since 28 Jul 2025: it is known to be exploited.
CVSS score 10.0: 9.0 or more.
CVSS score 10.0 (7.0 or more) and EPSS 0.98 (0.1 or more): a high score and a real chance of exploitation in the next 30 days.

Published by the CVE Program (CNA: cisco) at 25 Jun 2025, 16:11 UTC. agentprime has not analysed this yet, so whether it affects any app is not known. This CVE names a vendor and product rather than a package, so the lockfile check doesn’t match it.

Affected products, as the CNA wrote them
Vendor	Product	Versions
Cisco	Cisco Identity Services Engine Software	affected 3.3.0 affected 3.3 Patch 2 affected 3.3 Patch 1 affected 3.3 Patch 3 affected 3.4.0 affected 3.3 Patch 4 affected 3.4 Patch 1 affected 3.3 Patch 5 affected 3.3 Patch 6 Other versions: unknown

Identifiers: CVE-2025-20281
CNA: cisco
Weakness (CWE): CWE-74
Tags: Cisco Identity Services Engine Software
Other injection
Published: 25 Jun 2025
Updated: 26 Feb 2026

Not analysed yet

We haven’t published our own analysis of this CVE. If a person reviews it, this page will say what’s affected and what has to be true for it to matter.

Severity and exploitation

Score	Rating	CVSS	Vector	Source
10.0	Critical	3.1	CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:C/C:H/I:H/A:H	CNA (cisco)

CISA KEV Listed since 28 Jul 2025: known to be exploited.
EPSS 0.98, the 99th percentile, on 5 Nov 2026: FIRST’s estimate of the chance of exploitation in the next 30 days.

Timeline

This record came from the full history of the CVE Program, published 25 Jun 2025. New records show when each source confirmed them.

Sources

References from the CNA

sec.cloudapps.cisco.com/security/center/content/CiscoSecurityAdvisory/cisco-sa-ise-unauth-rce-ZAd2GnJ6

Facts on this page come from the CVE List as the CNA published them, with CVSS from the sources named above, CISA KEV and FIRST EPSS. Vendors, products and versions are shown as the CNA wrote them. We don’t reproduce the CVE’s description.