# MONAI: Unsafe functions lead to pickle deserialization rce

Advisory record · `GHSA-89gg-p5r5-q6r4`

- **Identifiers:** `GHSA-89gg-p5r5-q6r4` · `CVE-2026-100846` · `PYSEC-2026-4021`
- **State:** Confirmed
- **Severity:** CVSS 8.8 High
- **Critical:** No
- **Weakness (CWE):** [CWE-502](https://cwe.mitre.org/data/definitions/502.html)
- **Tags:** [Insecure deserialization](https://agentprime.io/advisories/tag/deserialization.md)
- **Published:** 7 Apr 2026
- **Updated:** 1 Oct 2026
- **Reviewed by a person:** No

Published by the GitHub Advisory Database at 7 Apr 2026, 20:17 UTC. agentprime has not analysed this yet, so whether it affects any app is not known.

## Affected packages

- `monai` (PyPI): affected `<1.6.0`; fixed in `1.6.0`

## Not analysed yet

We haven’t published our analysis of this Advisory yet. Once a person has reviewed it, this page will say what’s vulnerable, what has to be true for your app to be affected, and how to check.

## Severity and exploitation

- 8.8 High, CVSS 4.0: `CVSS:4.0/AV:N/AC:H/AT:P/PR:H/UI:P/VC:H/VI:H/VA:H/SC:H/SI:H/SA:H`, from CNA (VulnCheck)

- **CISA KEV:** Not listed.
- **EPSS:** 0.0036, the 30th percentile, on 12 Nov 2026: FIRST’s estimate of the chance of exploitation in the next 30 days.

## Timeline

- 31 Oct 2026, 14:09 UTC: First seen by agentprime
- 31 Oct 2026, 14:09 UTC: [Confirmed by OSV](https://osv.dev/vulnerability/GHSA-89gg-p5r5-q6r4)

## Sources

- [GitHub Advisory Database: GHSA-89gg-p5r5-q6r4](https://github.com/advisories/GHSA-89gg-p5r5-q6r4)
- [OSV: GHSA-89gg-p5r5-q6r4](https://osv.dev/vulnerability/GHSA-89gg-p5r5-q6r4)
- <https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-89gg-p5r5-q6r4>
- <https://github.com/Project-MONAI/MONAI/issues/8874#issuecomment-4752023161>
- <https://github.com/Project-MONAI/MONAI/commit/9078a72f3992e49bd4560db510be9ec4ccf972cc>
- <https://github.com/Project-MONAI/MONAI>
- <https://github.com/Project-MONAI/MONAI/releases/tag/1.6.0>

Facts on this page come from the GitHub Advisory Database (CC-BY 4.0), OSV and the other sources listed, as published. We don’t reproduce full advisory descriptions, which can contain exploit code.

## Check whether this affects you

A Match means an installed version is in the affected range above. Most don’t affect the app; agentprime hasn’t analysed this one yet.

- With the agentprime MCP server (<https://api.agentprime.io/mcp>), ask your agent to check the project: `check_lockfile` sends a lockfile, `check_packages` a list of installed packages, and both return the Matches and the upgrades that clear them. `get_advisory` returns this record. Setup: <https://agentprime.io/mcp.md>
- In a browser: <https://agentprime.io/check/> reads your lockfile in the browser, never uploading it.
- Whether it touches your code, with file and line: the Claude Code plugin, <https://agentprime.io/plugin.md>
- As JSON: <https://api.agentprime.io/v1/advisories/GHSA-89gg-p5r5-q6r4>, or `POST https://api.agentprime.io/v1/match` with your packages (<https://agentprime.io/api.md>)

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The web page: <https://agentprime.io/advisories/GHSA-89gg-p5r5-q6r4/>. Everything for agents: <https://agentprime.io/llms.txt>.